Since mid-October, protesters and police have routinely clashed in Tirana in anti-government demonstrations that morphed from rallies against a development linked to the family of US President Donald Trump.
Several government buildings have been attacked, dozens of demonstrators detained and more than 300 protestors and police injured, said the authorities.
On Saturday, police fired rubber bullets while some protesters used fireworks against the security forces.
"There is a lot of anger," said activist Sidorela Vatnikaj, labelling the movement a "revolution".
"It's not only a matter of students," she told AFP.
"It's not only a matter of environmental struggles... It's a matter of the state of rights and state of law."
The health ministry said 13 people were injured in Saturday's demonstrations, including nine demonstrators, two journalists and three police. Organisers called for fresh protests on Sunday from 1200 GMT.
Thousands of people heeded calls from organisers for students and others around Albania to attend Saturday's rally. Groups representing university professors, artists and opposition parties, had declared their support.
Many shops had closed ahead of the protests, some carrying signs on their shutters, such as: "Don't touch. We're with you."
Soon after the rally began outside the education ministry, a focal point for protests, a group of demonstrators hurled stones at the building, many of whose windows had been smashed in previous days, according to an AFP reporter.
Riot police immediately retaliated with water cannons, tear gas and rubber bullets.
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