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One vaccine may provide broad protection against many respiratory infections and allergens
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NomNom feddit.uk NomNom@feddit.uk
Joined: 2026-02-13
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196   Original
TheReturnOfPEB reddthat.com TheReturnOfPEB@reddthat.com
Joined: 2024-05-01
#2 · Quote Reply

still waiting on a poison ivy vaccine over here

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Lembot_0006 programming.dev Lembot_0006@programming.dev
Joined: 2025-12-08
#3 · Quote Reply

still waiting on a poison ivy vaccine over here

Not sure about the "ivy" part, but making a "poison" vaccine should be trivial.

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TheReturnOfPEB reddthat.com TheReturnOfPEB@reddthat.com
Joined: 2024-05-01
#4 · Quote Reply

Not sure about the "ivy" part, but making a "poison" vaccine should be trivial.

https://www.scientificamerican.com/article/a-vaccine-against-poison-ivy-misery-is-in-the-works-as-scientists-also-explore-new-treatment-paths/

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MyDogLovesMe lemmy.world MyDogLovesMe@lemmy.world
Joined: 2023-07-11
#5 · Quote Reply

My knee-jerk here is: “Ungh! United States? Not sure I trust that…”

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pageflight piefed.social pageflight@piefed.social
Joined: 2025-09-04
#6 · Quote Reply

Is it accurate to understand this as putting the lungs' immune response into a heightened state of response/alert? It doesn't sound like it's training the immune system about specific pathogens (or families of them). If that's true, why doesn't the body just do this already — is there a cost associated?

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themeatbridge lemmy.world themeatbridge@lemmy.world
Joined: 2023-06-28
#7 · Quote Reply

Is it accurate to understand this as putting the lungs' immune response into a heightened state of response/alert? It doesn't sound like it's training the immune system about specific pathogens (or families of them). If that's true, why doesn't the body just do this already — is there a cost associated?

Active macrophages can damage healthy cells. It's a very serious condition when they do, and it can lead to runaway cellular death. It doesn't mean that this treatment will cause MAS, but it's a risk that should be investigated with human trials.

It also has a metabolic cost, in that the active cells consume energy and oxygen, but I don't know if it would be a noticeable effect for the average person.

My guess is that this would be something you use when you are at increased risk for cold and flu. Like nurses and doctors, teachers and childcare workers, and nursing home staff during the fall and winter.

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themeatbridge lemmy.world themeatbridge@lemmy.world
Joined: 2023-06-28
#8 · Quote Reply

My knee-jerk here is: “Ungh! United States? Not sure I trust that…”

They're including a tracking chip in the vaccine. I learned about this on the Google News app I have installed on my cell phone, television, computer, car, gaming systems, smarthome appliances, and eyeglasses.

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Kirp123 lemmy.world Kirp123@lemmy.world
Joined: 2025-02-06
#9 · Quote Reply

Active macrophages can damage healthy cells. It's a very serious condition when they do, and it can lead to runaway cellular death. It doesn't mean that this treatment will cause MAS, but it's a risk that should be investigated with human trials. It also has a metabolic cost, in that the active cells consume energy and oxygen, but I don't know if it would be a noticeable effect for the average ...

Yeah, active macrophages will release cytokines and other inflammatory substances. Prolonged inflammation is linked with increased rates of cancer.

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Levi lemmy.ca Levi@lemmy.ca
Joined: 2025-03-09
#10 · Quote Reply

Is it accurate to understand this as putting the lungs' immune response into a heightened state of response/alert? It doesn't sound like it's training the immune system about specific pathogens (or families of them). If that's true, why doesn't the body just do this already — is there a cost associated?

I was thinking the same thing. There probably is a downside to having the innate immune system active 24/7, even if we don't know what it is yet.

A magical nasal spray that gets rid of allergies for 3 months sure does sound nice though.

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Evil_Incarnate sopuli.xyz Evil_Incarnate@sopuli.xyz
Joined: 2025-06-04
#11 · Quote Reply

Active macrophages can damage healthy cells. It's a very serious condition when they do, and it can lead to runaway cellular death. It doesn't mean that this treatment will cause MAS, but it's a risk that should be investigated with human trials. It also has a metabolic cost, in that the active cells consume energy and oxygen, but I don't know if it would be a noticeable effect for the average ...

I refuse to get flu shots simply because I'd rather feel like shit and sit at home for a few days than go to work.

But I still get paid for those days, people in less developed countries don't, so have only the option to work while sick or get the jab and work. Or starve.

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Evil_Incarnate sopuli.xyz Evil_Incarnate@sopuli.xyz
Joined: 2025-06-04
#12 · Quote Reply

still waiting on a poison ivy vaccine over here

Ask my dog, he sticks his nose in nettles all summer.

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😈MedicPig🐷BabySaver😈 lemmy.world MedicPigBabySaver@lemmy.world
Joined: 2023-07-04
#13 · Quote Reply

I refuse to get flu shots simply because I'd rather feel like shit and sit at home for a few days than go to work. But I still get paid for those days, people in less developed countries don't, so have only the option to work while sick or get the jab and work. Or starve.

Stupid.

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themeatbridge lemmy.world themeatbridge@lemmy.world
Joined: 2023-06-28
#14 · Quote Reply

I refuse to get flu shots simply because I'd rather feel like shit and sit at home for a few days than go to work. But I still get paid for those days, people in less developed countries don't, so have only the option to work while sick or get the jab and work. Or starve.

Or you could get the vaccine, don't get sick, and take a few days off while healthy.

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LurkingLuddite piefed.social LurkingLuddite@piefed.social
Joined: 2026-02-04
#15 · Quote Reply

Is it accurate to understand this as putting the lungs' immune response into a heightened state of response/alert? It doesn't sound like it's training the immune system about specific pathogens (or families of them). If that's true, why doesn't the body just do this already — is there a cost associated?

Autoimmune diseases are most often caused by an overactive immune system. I don't expect this development to go well for most people in the long term.

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pageflight piefed.social pageflight@piefed.social
Joined: 2025-09-04
#16 · Quote Reply

I refuse to get flu shots simply because I'd rather feel like shit and sit at home for a few days than go to work. But I still get paid for those days, people in less developed countries don't, so have only the option to work while sick or get the jab and work. Or starve.

I was hesitant to get the vaccine when I was just making a personal tradeoff. Seeing the whole "flatten the curve" catastrophe of COVID, and the resurgence of measles now, I think the major benefit is herd immunity / protecting vulnerable individuals.

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Evil_Incarnate sopuli.xyz Evil_Incarnate@sopuli.xyz
Joined: 2025-06-04
#17 · (edited) Quote Reply

Or you could get the vaccine, don't get sick, and take a few days off while healthy.

How do I get a doctor to sign off on sick leave when I'm healthy?

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hector lemmy.today hector@lemmy.today
Joined: 2025-09-03
#18 · Quote Reply

I'd previously read the innate immune system boost from the TB vaccine, and the polio vaccine, lasted a lifetime. People with the TB vaccine have lower health ailments across the board, and it's been borne out by multiple unrelated studies, according to a series of articles published in the Times in the spring of 2020. Their definition of innate immunity wasn't quite the way the article is describing it either they called the lifelong health benefits of the TB and Polio vaccines as innate immunity. They also said we didn't really know why it helps we only have a vague idea.

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themeatbridge lemmy.world themeatbridge@lemmy.world
Joined: 2023-06-28
#19 · Quote Reply

How do I get a doctor to sign off on sick leave when I'm healthy?

You need a doctor to sign off when you have a cold? What a shitty employer you must have.

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TigerAce lemmy.dbzer0.com TigerAce@lemmy.dbzer0.com
Joined: 2025-06-13
#20 · Quote Reply

This almost sounds too good to be true. Amazing! I hope it doesn't have downsides and will be affordable for everyone.

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Evil_Incarnate sopuli.xyz Evil_Incarnate@sopuli.xyz
Joined: 2025-06-04
#21 · Quote Reply

You need a doctor to sign off when you have a cold? What a shitty employer you must have.

Considering we get all the sick days we need and get paid for them all, it's a small price to pay (doctors visit is paid for by the employer). This is separate from our 5 weeks of paid holidays each year.

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