My area needs this sooooo bad. We have one of the highest Lyme disease rates in the country. Unfortunately, Alpha-gal disease is now also in this area, so even with this vaccine, every family walk even near the woods or fields still has to be followed with full body and hair inspections. Every time. So many ticks... Ugh.

Here it's Lyme and tick-borne encephalitis. You can get vaccinated against the latter but a lot of people don't bother or don't know. And we have a LOT of ticks.

Frickin finally

You need more urban foxes to prevent the spread of rodents and wolves to prevent the spread of deer. Both of those predators can curb or slow the spread of ticks and tick-borne diseases. A lot of rodents serve as tick highways to spread into new areas, which is how the lone star ticks are starting to really make their way into new regions.

CWD, a prion disease, is spreading through deer and elk out here in the west, but wolves are immune to it and other diseases.

Y'all forgetting that the FDA is currently run by an insane, leathery ball sack.

Who hired, fired, hired and fired the same guy in 12 months.

Then, there was a guy soliciting bribes.

Unfortunately, there is no evidence the vaccine actually works.

My wife & I both volunteered for this study. Hope it gets approved ASAP!

And opossums to eat the ticks that do make it there.

This is relating to requesting additional clinical trials, but maybe I don't understand?

Could you elaborate?

Edit: looks like it's actually a request for approval for commercialization/use of the vaccine. Not sure what I was doing when I looked the first time.

And the article linked in the OP states:

"Pfizer said it will seek regulatory approval for a Lyme disease vaccine candidate despite failing a late-stage trial.

Pfizer said not enough people contracted Lyme disease to be confident in the results, but cited “strong efficacy” for its decision to move forward."

Which is sort of different wording of what the OP does still say, so, yeah, some doubt's about it. I can see some desire to have additional studies at least.

False opossums the ugly fucks, so ugly that its cute. don't actively feed on ticks. Just what ever ones they find on themselves at the time.

The articles I catch about tick diseases cite global warming changing ticks' active season and breeding patterns, not overabundance of host animals.
Not that I'm disagreeing, necessarily. I see lots of deer and rabbits, anecdotaly, more than would normally roam together if active predators were around. The urban hawks and foxes do at least seem to be taking advantage of the rabbit buffet in my neighborhood (I see them regularly, which is amazing), but yeah, no wolves roaming my suburbs.
What's your theory as to why under-predation isn't getting cited? Families just wouldn't be ok with living in proximity with wild wolves so it's just not a solution that can be presented by media?