Granted. Civilization and ecosystems immediately collapse as everything is in a constant state of climax. Hundreds of millions of people die in car, airplane and even train crashes. Rest is going to die soon due to cardiac arrests, dehydration and kidney failures.

Granted. The driving force for human advancement ceases and technological progress grinds to a halt. Hedonism grips the population and the long term rewarding efforts such as art are abandoned in favor of revelry. There is endless pleasure yes, but no satisfaction.

how does that minimise suffering? I can think of a more minimal state

You never specified a duration. The suffering here could be minimal relative to the immense pleasure of the human species shortly before death

I'd rather say that pleasure is simply too great to notice that one's about to flatline, so people just go like that.

Hot

Granted, emotions have been removed due to the likelihood of emotional suffering. All fatal diseases and injuries are now immediately fatal regardless of initial onset duration.

Granted, every sentient being immediately dies so they can no longer suffer

Everything capable of suffering dies.

The few things that fit the latter condition die of starvation, some time later.

you didn’t specify how long the suffering was minimized

Their deaths are quick. They did not suffer.

Granted.. They all die from inhaling nitrous oxide. Haha.

But they all cum first like in "never stop blowing up"

Granted.

Everyone, everywhere; from those on death's door from age or illness down to fetuses with enough nervous system to feel anything have a sudden cessation of pain, depression, anxiety, or other forms of suffering.

They then begin non stop orgasms that, despite slowly staving to death and dehydrating, leave them in total bliss until they die.

Boy- and Girl-Cum floods the streets. No regrets.

Edit: This is probably the worst thing I've ever written.